2. Gene
  3. Defa4 - defensin, alpha, 4 Gene

Defa4 - defensin, alpha, 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Crp4; Defa28; Defcr4

Gene ID: 13238 | Gene type: protein coding

About Defa4

Summary

Enables phospholipid binding activity. Involved in killing of cells of Other organism. Acts upstream of or within Antibacterial humoral response and membrane disruption in Other organism. Located in extracellular space. Is expressed in duodenum and ileum. Orthologous to several human genes including DEFA4 (defensin alpha 4) and DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Apr 2022]

Defa4 Products(2)

mRNA Protein Name
NM_010039.2 NP_034169.2 defensin alpha 4 precursor
NM_010039.2 NP_034169.2 defensin alpha 4 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables phospholipid binding IDA
IDA: Inferred from direct assay
12574157 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within antibacterial humoral response IDA
IDA: Inferred from direct assay
21041494 MGI
acts upstream of or within defense response to bacterium IDA
IDA: Inferred from direct assay
7927786 MGI
involved in defense response to bacterium IMP
IMP: Inferred from mutant phenotype
15297466 MGI
acts upstream of or within disruption of plasma membrane integrity in another organism IDA
IDA: Inferred from direct assay
20056603 MGI
involved in killing of cells of another organism IMP
IMP: Inferred from mutant phenotype
15297466 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
21041494 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

defensin alpha 4

alpha-defensin 4

alpha-defensin, 28

defensin related cryptdin 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03675 DEFA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Defa4 NCBI NCBI:1669