GRPEL2 - GrpE like 2, mitochondrial Gene

Also Known as Mt-GrpE#2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 134266

About GRPEL2

Cytogenetic location: 5q32 Genomic coordinates (GRCh38): 5:149,345,499-149,354,583 (from NCBI)

This gene has 4 transcripts (splice variants), 170 orthologues and 1 paralogue. Ubiquitous expression in esophagus (RPKM 15.4), fat (RPKM 4.6) and 24 other tissues.

Summary

Predicted to enable adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

GRPEL2 Products (1)

mRNA Protein Name
NM_152407.4 NP_689620.2 grpE protein homolog 2, mitochondrial precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GRPEL2 Protein Structure

GrpE

GrpE: GrpE (58 - 218)

  • 0
  • 100
  • 200
  • 225 a.a.
Protein Preferred Names Protein Names

grpE protein homolog 2, mitochondrial

GRPEL2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GRPEL2 Q8TAA5 DBT Homo sapiens P11182
Anti Tag CoIP
33961781
Intra
GRPEL2 Q8TAA5 DBT Homo sapiens P11182
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Freemartinism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05846 GRPEL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus GRPEL2 VGNC VGNC:102218
Rattus norvegicus GRPEL2 RGD RGD:1585231
Mus musculus GRPEL2 MGD MGI:1334416
Canis familiaris GRPEL2 VGNC VGNC:41518
Macaca mulatta GRPEL2 VGNC VGNC:73208
Others GRPEL2 NCBI