Doc2b - double C2, beta Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13447

Summary

The protein encoded by this gene is a calcium sensor involved in glucose-stimulated Insulin secretion, spontaneous neurotransmitter release, and enhanced SNARE-dependent vesicle fusion. [provided by RefSeq, Sep 2015]

Doc2b Products (1)

mRNA Protein Name
NM_007873.3 NP_031899.2 double C2-like domain-containing protein beta

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
21521611 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17548353 MGI
enables syntaxin binding IPI
IPI: Inferred from physical interaction
19033398 MGI
Biological Process GO Annotation Evidence References Source
involved in calcium ion-regulated exocytosis of neurotransmitter IMP
IMP: Inferred from mutant phenotype
20150444 MGI
involved in calcium-dependent activation of synaptic vesicle fusion IDA
IDA: Inferred from direct assay
20150444 MGI
involved in calcium-dependent activation of synaptic vesicle fusion IMP
IMP: Inferred from mutant phenotype
20150444 MGI
involved in positive regulation of insulin secretion IMP
IMP: Inferred from mutant phenotype
17548353 MGI
involved in protein localization IMP
IMP: Inferred from mutant phenotype
19033398 MGI
acts upstream of or within spontaneous neurotransmitter secretion IDA
IDA: Inferred from direct assay
21521611 MGI
acts upstream of or within spontaneous neurotransmitter secretion IGI
IGI: Inferred from genetic interaction
21521611 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19033398 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
19033398 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

double C2-like domain-containing protein beta

  • doc2-beta

  • double C2 protein beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03920 DOC2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Doc2b NCBI NCBI:8447