Dok2 - docking protein 2 Gene

Also Known as DokR; Frip; dok-R

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13449

Summary

Enables transmembrane receptor protein tyrosine kinase adaptor activity. Acts upstream of or within Ras protein signal transduction and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be active in cytoplasm. Is expressed in heart; lung; lymph node; spleen; and thymus. Orthologous to human DOK2 (docking protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Dok2 Products (3)

mRNA Protein Name
NM_001401280.1 NP_001388209.1 docking protein 2 isoform 2
NM_001401281.1 NP_001388210.1 docking protein 2 isoform 2
NM_010071.3 NP_034201.1 docking protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9697832 MGI
enables transmembrane receptor protein tyrosine kinase adaptor activity IPI
IPI: Inferred from physical interaction
10428862 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Ras protein signal transduction IPI
IPI: Inferred from physical interaction
9697832 MGI
acts upstream of or within cell surface receptor protein tyrosine kinase signaling pathway IPI
IPI: Inferred from physical interaction
9697832 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

docking protein 2

  • IL-four receptor-interacting protein

  • dok-related protein

  • downstream of tyrosine kinase 2

  • p56(dok-2)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03934 DOK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992162 23ME-00610 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dok2 NCBI NCBI:9046