Elf5 - E74-like factor 5 Gene

Also Known as ESE-2; ESE-5; ESE-5.

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13711

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including ectodermal cell fate commitment; mammary gland epithelial cell differentiation; and somatic stem cell population maintenance. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; integumental system; and respiratory system epithelium. Orthologous to human ELF5 (E74 like ETS transcription factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Elf5 Products (2)

mRNA Protein Name
NM_001145813.1 NP_001139285.1 ETS-related transcription factor Elf-5
NM_010125.3 NP_034255.2 ETS-related transcription factor Elf-5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
9840936 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
9840936 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within ectoderm development IMP
IMP: Inferred from mutant phenotype
15829518 MGI
acts upstream of or within ectodermal cell fate commitment IGI
IGI: Inferred from genetic interaction
25446535 MGI
acts upstream of or within mammary gland epithelial cell differentiation IGI
IGI: Inferred from genetic interaction
16469767 MGI
acts upstream of or within negative regulation of cell differentiation involved in embryonic placenta development IMP
IMP: Inferred from mutant phenotype
24859262 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9840936 MGI
acts upstream of or within somatic stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
24859262 MGI
acts upstream of trophoblast giant cell differentiation IMP
IMP: Inferred from mutant phenotype
24859262 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16469767 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16469767 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ETS-related transcription factor Elf-5

  • Epithelium specific Ets-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04302 ELF5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elf5 NCBI NCBI:2001