Eps15l1 - epidermal growth factor receptor pathway substrate 15-like 1 Gene

Mus musculus

Also known as Eps15R; Eps15-rs; 9830147J04Rik

Gene ID: 13859 | Gene type: protein coding

About Eps15l1

Summary

Predicted to enable calcium ion binding activity. Predicted to be involved in endocytosis and endosomal transport. Part of clathrin coat of coated pit. Is expressed in several structures, including alimentary system; liver; metanephros; nervous system; and sensory organ. Orthologous to human EPS15L1 (epidermal growth factor receptor pathway substrate 15 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Eps15l1 Products(3)

mRNA	Protein	Name
NM_001122832.1	NP_001116304.1	epidermal growth factor receptor substrate 15-like 1 isoform b
NM_001289859.1	NP_001276788.1	epidermal growth factor receptor substrate 15-like 1 isoform c
NM_007944.3	NP_031970.2	epidermal growth factor receptor substrate 15-like 1 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	9446614	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in synaptic vesicle endocytosis	IDA IDA: Inferred from direct assay	30692166	MGI
involved in synaptic vesicle endocytosis	IEP IEP: Inferred from expression pattern	30692166	MGI
involved in synaptic vesicle endocytosis	IMP IMP: Inferred from mutant phenotype	30692166	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of clathrin coat of coated pit	IDA IDA: Inferred from direct assay	18434600	MGI
is active in presynapse	IDA IDA: Inferred from direct assay	30692166	MGI
is active in presynapse	IEP IEP: Inferred from expression pattern	30692166	MGI
is active in presynapse	IMP IMP: Inferred from mutant phenotype	30692166	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

epidermal growth factor receptor substrate 15-like 1

epidermal growth factor receptor pathway substrate 15-related sequence

eps15-related protein

Eps15l1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Eps15l1	Q60902	Eps15	Mus musculus	P42567	CoIP	9446614

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04453	EPS15L1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Eps15l1	NCBI	NCBI:58513

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