Eps15l1 - epidermal growth factor receptor pathway substrate 15-like 1 Gene

Also Known as Eps15R; Eps15-rs; 9830147J04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13859

Summary

Predicted to enable calcium ion binding activity. Predicted to be involved in endocytosis and endosomal transport. Part of clathrin coat of coated pit. Is expressed in several structures, including alimentary system; liver; metanephros; nervous system; and sensory organ. Orthologous to human EPS15L1 (epidermal growth factor receptor pathway substrate 15 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Eps15l1 Products (3)

mRNA Protein Name
NM_001122832.1 NP_001116304.1 epidermal growth factor receptor substrate 15-like 1 isoform b
NM_001289859.1 NP_001276788.1 epidermal growth factor receptor substrate 15-like 1 isoform c
NM_007944.3 NP_031970.2 epidermal growth factor receptor substrate 15-like 1 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9446614 MGI
Biological Process GO Annotation Evidence References Source
involved in synaptic vesicle endocytosis IDA
IDA: Inferred from direct assay
30692166 MGI
involved in synaptic vesicle endocytosis IEP
IEP: Inferred from expression pattern
30692166 MGI
involved in synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
30692166 MGI
Cellular Component GO Annotation Evidence References Source
part of clathrin coat of coated pit IDA
IDA: Inferred from direct assay
18434600 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
30692166 MGI
is active in presynapse IEP
IEP: Inferred from expression pattern
30692166 MGI
is active in presynapse IMP
IMP: Inferred from mutant phenotype
30692166 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

epidermal growth factor receptor substrate 15-like 1

  • epidermal growth factor receptor pathway substrate 15-related sequence

  • eps15-related protein

Eps15l1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Eps15l1 Q60902 Eps15 Mus musculus P42567
CoIP
9446614
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04453 EPS15L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eps15l1 NCBI NCBI:58513