Chchd2 - coiled-coil-helix-coiled-coil-helix domain containing 2 Gene

Predicted to enable DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Predicted to be involved in several processes, including cellular response to oxidative stress; positive regulation of mitochondrial ATP synthesis coupled electron transport; and regulation of cellular response to hypoxia. Located in mitochondrion. Is expressed in several structures, including diaphragm; gonad; head mesenchyme; heart ventricle; and vertebral axis musculature. Human ortholog(s) of this gene implicated in Parkinson's disease 22. Orthologous to human CHCHD2 (coiled-coil-helix-coiled-coil-helix domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]