Eya3 - EYA transcriptional coactivator and phosphatase 3 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14050

Summary

Enables chromatin binding activity; protein tyrosine Phosphatase activity; and protein tyrosine/serine/threonine Phosphatase activity. Acts upstream of or within protein dephosphorylation. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including branchial arch; genitourinary system; limb bud; rhombomere; and sensory organ. Orthologous to human EYA3 (EYA transcriptional coactivator and Phosphatase 3). [provided by Alliance of Genome Resources, Apr 2022]

Eya3 Products (9)

mRNA Protein Name
NM_001403755.1 NP_001390684.1 eyes absent homolog 3 isoform 4
NM_001403756.1 NP_001390685.1 eyes absent homolog 3 isoform 4
NM_001403757.1 NP_001390686.1 eyes absent homolog 3 isoform 5
NM_001403758.1 NP_001390687.1 eyes absent homolog 3 isoform 6
NM_001403759.1 NP_001390688.1 eyes absent homolog 3 isoform 7
NM_001403760.1 NP_001390689.1 eyes absent homolog 3 isoform 8
NM_010166.4 NP_034296.2 eyes absent homolog 3 isoform 2
NM_210071.3 NP_997592.1 eyes absent homolog 3 isoform 1
NM_211357.3 NP_997596.1 eyes absent homolog 3 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IGI
IGI: Inferred from genetic interaction
19008232 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12215533 MGI
enables protein tyrosine phosphatase activity IDA
IDA: Inferred from direct assay
14628052 MGI
enables protein tyrosine/serine/threonine phosphatase activity IDA
IDA: Inferred from direct assay
14628042 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein dephosphorylation IDA
IDA: Inferred from direct assay
14628052 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
14628042 MGI
part of transcription regulator complex IPI
IPI: Inferred from physical interaction
19008232 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eyes absent homolog 3

  • eyes absent 3 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-135774 6-Hydroxybenzbromarone Inhibitor 99.96% Unkown
HY-RS04613 EYA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eya3 NCBI NCBI:2140