2. Gene
  3. Eya4 - EYA transcriptional coactivator and phosphatase 4 Gene

Eya4 - EYA transcriptional coactivator and phosphatase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as B130023L16Rik

Gene ID: 14051 | Gene type: protein coding

About Eya4

Summary

Predicted to enable protein tyrosine Phosphatase activity. Acts upstream of or within middle ear morphogenesis and sensory perception of sound. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; limb bud; sensory organ; and urinary system. Used to study otitis media. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 10; congestive heart failure; dilated cardiomyopathy; dilated cardiomyopathy 1J; and sensorineural hearing loss. Orthologous to human EYA4 (EYA transcriptional coactivator and Phosphatase 4). [provided by Alliance of Genome Resources, Apr 2022]

Eya4 Products(2)

mRNA Protein Name
NM_001347372.1 NP_001334301.1 eyes absent homolog 4 isoform 2
NM_010167.5 NP_034297.2 eyes absent homolog 4 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within middle ear morphogenesis IMP
IMP: Inferred from mutant phenotype
18219393 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
18219393 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eyes absent homolog 4

eyes absent 4 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04614 EYA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eya4 NCBI NCBI:2070