F13b - coagulation factor XIII, beta subunit Gene

Also Known as Cf13b; Cf-13b

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 14060

Summary

This gene encodes subunit B of the coagulation factor XIII that catalyzes the final step of the blood coagulation pathway. The encoded protein associates with subunit A to form a heterotetrameric protein that circulates in the plasma. During the blood coagulation process, thrombin-mediated proteolytic cleavage of the subunit A results in the dissociation of the encoded protein from the heterotetramer. Male mice lacking the encoded protein exhibit mild fibrosis together with hemosiderin deposits in the heart. [provided by RefSeq, Sep 2015]

F13b Products (1)

mRNA Protein Name
NM_031164.2 NP_112441.2 coagulation factor XIII B chain precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
18224415 MGI
Biological Process GO Annotation Evidence 参考文献 由来
involved in blood coagulation IMP
IMP: Inferred from mutant phenotype
18224415 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coagulation factor XIII B chain

  • protein-glutamine gamma-glutamyltransferase B chain

  • transglutaminase B chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS04629 F13B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17536 F13b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23993 F13b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens F13b NCBI NCBI:2165