ISM1 - isthmin 1 Gene

Also Known as ISM; Isthmin; C20orf82; bA149I18.1; dJ1077I2.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 140862

About ISM1

Cytogenetic location: 20p12.1 Genomic coordinates (GRCh38): 20:13,221,274-13,326,723 (from NCBI)

This gene has 1 transcript (splice variant), 202 orthologues and 5 paralogues. Biased expression in thyroid (RPKM 10.3), placenta (RPKM 5.3) and 12 other tissues.

Summary

Predicted to be involved in negative regulation of angiogenesis. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

ISM1 Products (1)

mRNA Protein Name
NM_080826.2 NP_543016.1 isthmin-1 precursor

ISM1 Protein Structure

TSP_1

TSP_1: Thrombospondin type 1 domain (222 - 261)

AMOP

AMOP: AMOP domain (293 - 449)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 464 a.a.
Protein Preferred Names Protein Names

isthmin-1

  • isthmin 1 homolog

Recombinant ISM1 Proteins

Cat. No. Product Name Accession Purity
HY-P79426 ISM1 Protein, Human (HEK293, His) B1AKI9 (A30-Y464) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Non-Syndromic X-Linked Intellectual Disability 14

  • Mrx14
Cancerophobia

  • Cancer Phobia

  • Fear Of Getting Cancer
Nosophobia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06935 ISM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20757 Ism1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27270 Ism1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ISM1 VGNC VGNC:42111
Bos taurus ISM1 VGNC VGNC:30300
Rattus norvegicus ISM1 RGD RGD:1562551
Macaca mulatta ISM1 VGNC VGNC:73607
Felis catus ISM1 VGNC VGNC:62976
Mus musculus ISM1 MGD MGI:2442963
Others ISM1 NCBI