Arhgef5 - Rho guanine nucleotide exchange factor 5 Gene

Rattus norvegicus

Also known as Tim1

Gene ID: 140898 | Gene type: protein coding

About Arhgef5

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including activation of GTPase activity; positive regulation of JUN kinase activity; and positive regulation of stress fiber assembly. Predicted to act upstream of or within several processes, including hematopoietic stem cell homeostasis; myeloid dendritic cell chemotaxis; and positive regulation of podosome assembly. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm and nucleus. Orthologous to human ARHGEF5 (Rho guanine nucleotide exchange factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Arhgef5 Products(2)

mRNA	Protein	Name
XM_342676.9	XP_342677.5	rho guanine nucleotide exchange factor 5
XM_039108652.1	XP_038964580.1	rho guanine nucleotide exchange factor 5

Protein Preferred Names

Protein Names

rho guanine nucleotide exchange factor 5

Rho guanine nucleotide exchange factor (GEF) 5

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00962	ARHGEF5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Arhgef5	NCBI	NCBI:7984

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