Dclre1b - DNA cross-link repair 1B Gene

Also Known as SNMIB; Apollo; mSNM1B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 140917

Summary

Enables 5'-3' exonuclease activity. Involved in protection from non-homologous end joining at telomere; telomeric 3' overhang formation; and telomeric loop formation. Located in chromosome, telomeric region. Is expressed in brain. Orthologous to human DCLRE1B (DNA cross-link repair 1B). [provided by Alliance of Genome Resources, Apr 2022]

Dclre1b Products (4)

mRNA Protein Name
NM_001025312.1 NP_001020483.1 5' exonuclease Apollo isoform b
NM_133865.2 NP_598626.2 5' exonuclease Apollo isoform a
NM_001025312.1 NP_001020483.1 5' exonuclease Apollo isoform b
NM_133865.2 NP_598626.2 5' exonuclease Apollo isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 5'-3' exonuclease activity IMP
IMP: Inferred from mutant phenotype
20551906 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20619712 MGI
Biological Process GO Annotation Evidence References Source
involved in protection from non-homologous end joining at telomere IMP
IMP: Inferred from mutant phenotype
20551906 MGI
involved in telomeric 3' overhang formation IMP
IMP: Inferred from mutant phenotype
20551906 MGI
involved in telomeric loop formation IMP
IMP: Inferred from mutant phenotype
20619712 MGI
Cellular Component GO Annotation Evidence References Source
located in chromosome, telomeric region IDA
IDA: Inferred from direct assay
20551906 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

5' exonuclease Apollo

  • DNA cross-link repair 1B protein

  • DNA cross-link repair 1B, PSO2 homolog

  • SNM1 homolog B

  • beta-lactamase MBLAC2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03581 DCLRE1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dclre1b NCBI NCBI:64858