Slc17a6 - solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 Gene
Also Known as DNPI; VGLUT2; 2900073D12Rik
Species: Mus musculus
Summary
Enables L-glutamate transmembrane transporter activity. Involved in hyaloid vascular plexus regression. Acts upstream of or within neurotransmitter uptake. Located in synaptic vesicle. Is expressed in several structures, including cranial ganglion; nervous system; sensory organ; tail mesenchyme; and testis. Orthologous to human SLC17A6 (solute carrier family 17 member 6). [provided by Alliance of Genome Resources, Apr 2022]
Slc17a6 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001355150.1 | NP_001342079.1 | vesicular glutamate transporter 2 isoform 2 |
| NM_080853.3 | NP_543129.3 | vesicular glutamate transporter 2 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables L-glutamate uniporter activity |
IDA
IDA: Inferred from direct assay
|
11432869 | MGI |
| enables potassium:proton antiporter activity |
IDA
IDA: Inferred from direct assay
|
25433636 | MGI |
| enables sodium:phosphate symporter activity |
IDA
IDA: Inferred from direct assay
|
33440152 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in L-glutamate transmembrane transport |
IMP
IMP: Inferred from mutant phenotype
|
11432869 | MGI |
| involved in hyaloid vascular plexus regression |
IMP
IMP: Inferred from mutant phenotype
|
30936473 | MGI |
| acts upstream of or within neurotransmitter uptake |
IDA
IDA: Inferred from direct assay
|
11432869 | MGI |
| involved in phosphate ion homeostasis |
IDA
IDA: Inferred from direct assay
|
33440152 | MGI |
| involved in sodium-dependent phosphate transport |
IDA
IDA: Inferred from direct assay
|
33440152 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in presynapse |
IDA
IDA: Inferred from direct assay
|
29465786 | MGI |
| located in synaptic vesicle |
IDA
IDA: Inferred from direct assay
|
11432869 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
vesicular glutamate transporter 2 |
|
|
Slc17a6 Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P87139 | VGLUT2 Antibody (YA6832) | WB, IHC-F, IHC-P | Mouse, Rat |