2. Gene
  3. Fem1a - fem 1 homolog a Gene

Fem1a - fem 1 homolog a Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Eprap; Fem1aa

Gene ID: 14154 | Gene type: protein coding

About Fem1a

Summary

Predicted to enable EP4 subtype prostaglandin E2 receptor binding activity and ubiquitin ligase-substrate adaptor activity. Involved in positive regulation of inflammatory response. Acts upstream of or within negative regulation of MAP kinase activity and negative regulation of inflammatory response. Located in mitochondrion. Is expressed in several structures, including blastocyst; central nervous system; genitourinary system; retina; and spleen. Orthologous to human FEM1A (fem-1 homolog A). [provided by Alliance of Genome Resources, Apr 2022]

Fem1a Products(1)

mRNA Protein Name
NM_010192.4 NP_034322.3 protein fem-1 homolog A-A
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of MAP kinase activity IDA
IDA: Inferred from direct assay
18270204 MGI
acts upstream of or within negative regulation of inflammatory response IGI
IGI: Inferred from genetic interaction
18270204 MGI
involved in positive regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
27315781 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
19406122 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein fem-1 homolog A-A

FEM1-alpha-A

FEM1a-A

feminization 1 homolog a

prostaglandin E receptor 4-associated protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04860 FEM1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04858 FEM1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fem1a NCBI NCBI:55527