Fgf12 - fibroblast growth factor 12 Gene

Also Known as Fhf1; FHF-1; Fgf1a; FGF-12; B230343J05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14167

Summary

Predicted to enable heparin binding activity; Sodium Channel regulator activity; and transmembrane transporter binding activity. Acts upstream of or within several processes, including adult locomotory behavior; neuromuscular process; and positive regulation of sodium ion transport. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; limb; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 47. Orthologous to human FGF12 (Fibroblast Growth Factor 12). [provided by Alliance of Genome Resources, Apr 2022]

Fgf12 Products (5)

mRNA Protein Name
NM_001276419.2 NP_001263348.1 fibroblast growth factor 12 isoform c
NM_001276420.1 NP_001263349.1 fibroblast growth factor 12 isoform d
NM_001357064.1 NP_001343993.1 fibroblast growth factor 12 isoform e
NM_010199.4 NP_034329.1 fibroblast growth factor 12 isoform b
NM_183064.5 NP_898887.1 fibroblast growth factor 12 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11376006 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adult locomotory behavior IGI
IGI: Inferred from genetic interaction
17678857 MGI
acts upstream of or within chemical synaptic transmission IGI
IGI: Inferred from genetic interaction
17678857 MGI
acts upstream of or within neuromuscular process IGI
IGI: Inferred from genetic interaction
17678857 MGI
acts upstream of or within positive regulation of sodium ion transport IGI
IGI: Inferred from genetic interaction
17678857 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 12

  • fibroblast growth factor 1a

  • fibroblast growth factor homologous factor 1

  • myocyte-activating factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04889 FGF12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174709 Human FGF12 mRNA / Unkown
HY-RS17830 Fgf12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24298 Fgf12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf12 NCBI NCBI:2257