Flot2 - flotillin 2 Gene

Also Known as Esa; reggie-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14252

Summary

Predicted to enable ionotropic glutamate receptor binding activity and protease binding activity. Involved in anterograde dendritic transport and regulation of postsynaptic membrane neurotransmitter receptor levels. Acts upstream of or within regulation of myoblast differentiation. Located in acrosomal membrane and caveola. Part of flotillin complex. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Orthologous to human FLOT2 (flotillin 2). [provided by Alliance of Genome Resources, Apr 2022]

Flot2 Products (7)

mRNA Protein Name
NM_001040403.2 NP_001035493.1 flotillin-2 isoform 1
NM_001284227.2 NP_001271156.1 flotillin-2 isoform 3
NM_001284228.3 NP_001271157.1 flotillin-2 isoform 2
NM_001362625.1 NP_001349554.1 flotillin-2 isoform 5
NM_001362626.1 NP_001349555.1 flotillin-2 isoform 2
NM_001362627.1 NP_001349556.1 flotillin-2 isoform 4
NM_008028.4 NP_032054.1 flotillin-2 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in anterograde dendritic transport IDA
IDA: Inferred from direct assay
27993509 MGI
involved in anterograde dendritic transport IMP
IMP: Inferred from mutant phenotype
27993509 MGI
involved in regulation of myoblast differentiation IEP
IEP: Inferred from expression pattern
25105415 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
27993509 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
27993509 MGI
Cellular Component GO Annotation Evidence References Source
located in acrosomal membrane IDA
IDA: Inferred from direct assay
19144954 MGI
located in caveola IDA
IDA: Inferred from direct assay
9153235 MGI
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
25105415 MGI
part of flotillin complex IDA
IDA: Inferred from direct assay
17600709 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27993509 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
27993509 MGI
located in membrane IDA
IDA: Inferred from direct assay
15886206 MGI
located in membrane raft IDA
IDA: Inferred from direct assay
12927782 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

flotillin-2

  • epidermal surface antigen

  • membrane component chromosome 17 surface marker 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04983 FLOT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Flot2 NCBI NCBI:2319