Cidec - cell death-inducing DFFA-like effector c Gene

Mus musculus

Also known as Fsp27; CIDE-3

Gene ID: 14311 | Gene type: protein coding

About Cidec

Summary

Predicted to be involved in execution phase of apoptosis; lipid droplet organization; and regulation of apoptotic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol. Is expressed in several structures, including alimentary system; endocrine gland; hemolymphoid system gland; integumental system; and reproductive system. Human ortholog(s) of this gene implicated in familial partial lipodystrophy type 5. Orthologous to human CIDEC (cell death inducing DFFA like effector c). [provided by Alliance of Genome Resources, Apr 2022]

Cidec Products(3)

mRNA	Protein	Name
NM_001301295.1	NP_001288224.1	cell death activator CIDE-3 isoform 1
NM_001372264.1	NP_001359193.1	cell death activator CIDE-3 isoform 2
NM_178373.4	NP_848460.1	cell death activator CIDE-3 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables lipid transfer activity	IDA IDA: Inferred from direct assay	22144693	MGI
enables molecular condensate scaffold activity	IDA IDA: Inferred from direct assay	34508658	MGI
enables phosphatidic acid binding	IDA IDA: Inferred from direct assay	26609809	MGI
enables phosphatidylinositol binding	IDA IDA: Inferred from direct assay	30361435	MGI
enables phosphatidylserine binding	IDA IDA: Inferred from direct assay	30361435	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in lipid droplet fusion	IDA IDA: Inferred from direct assay	22144693	MGI
involved in lipid storage	IDA IDA: Inferred from direct assay	22144693	MGI
involved in lipid storage	IMP IMP: Inferred from mutant phenotype	18682832	MGI
involved in negative regulation of lipid catabolic process	IDA IDA: Inferred from direct assay	22144693	MGI
involved in negative regulation of triglyceride metabolic process	IMP IMP: Inferred from mutant phenotype	18682832	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in lipid droplet	IDA IDA: Inferred from direct assay	22144693	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cell death activator CIDE-3

CIDE-3alpha	cell death-inducing DFFA-like effector protein C
fat specific gene 27	fat-specific protein FSP27

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02713	CIDEC Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cidec	NCBI	NCBI:63924

Name
Email *

	Sorry, but the email address you supplied was invalid.