Cidec - cell death-inducing DFFA-like effector c Gene

Also Known as Fsp27; CIDE-3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14311

Summary

Predicted to be involved in execution phase of apoptosis; lipid droplet organization; and regulation of apoptotic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol. Is expressed in several structures, including alimentary system; endocrine gland; hemolymphoid system gland; integumental system; and reproductive system. Human ortholog(s) of this gene implicated in familial partial lipodystrophy type 5. Orthologous to human CIDEC (cell death inducing DFFA like effector c). [provided by Alliance of Genome Resources, Apr 2022]

Cidec Products (3)

mRNA Protein Name
NM_001301295.1 NP_001288224.1 cell death activator CIDE-3 isoform 1
NM_001372264.1 NP_001359193.1 cell death activator CIDE-3 isoform 2
NM_178373.4 NP_848460.1 cell death activator CIDE-3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables lipid transfer activity IDA
IDA: Inferred from direct assay
22144693 MGI
enables molecular condensate scaffold activity IDA
IDA: Inferred from direct assay
34508658 MGI
enables phosphatidic acid binding IDA
IDA: Inferred from direct assay
26609809 MGI
enables phosphatidylinositol binding IDA
IDA: Inferred from direct assay
30361435 MGI
enables phosphatidylserine binding IDA
IDA: Inferred from direct assay
30361435 MGI
Biological Process GO Annotation Evidence References Source
involved in lipid droplet fusion IDA
IDA: Inferred from direct assay
22144693 MGI
involved in lipid storage IDA
IDA: Inferred from direct assay
22144693 MGI
involved in lipid storage IMP
IMP: Inferred from mutant phenotype
18682832 MGI
involved in negative regulation of lipid catabolic process IDA
IDA: Inferred from direct assay
22144693 MGI
involved in negative regulation of triglyceride metabolic process IMP
IMP: Inferred from mutant phenotype
18682832 MGI
Cellular Component GO Annotation Evidence References Source
is active in lipid droplet IDA
IDA: Inferred from direct assay
22144693 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell death activator CIDE-3

  • CIDE-3alpha

  • cell death-inducing DFFA-like effector protein C

  • fat specific gene 27

  • fat-specific protein FSP27

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02713 CIDEC Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cidec NCBI NCBI:63924