FGFBP3 - fibroblast growth factor binding protein 3 Gene

Also Known as FGF-BP3; C10orf13

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 143282

About FGFBP3

This gene has 1 transcript (splice variant), 133 orthologues and 2 paralogues. Biased expression in brain (RPKM 6.6), prostate (RPKM 0.9) and 13 other tissues.

Summary

Enables Fibroblast Growth Factor binding activity and heparin binding activity. Acts upstream of or within positive regulation of Fibroblast Growth Factor receptor signaling pathway and positive regulation of vascular permeability. Located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

FGFBP3 Products (1)

mRNA Protein Name
NM_152429.5 NP_689642.3 fibroblast growth factor-binding protein 3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables fibroblast growth factor binding IPI
IPI: Inferred from physical interaction
18669637 GOA
enables heparin binding IDA
IDA: Inferred from direct assay
18669637 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of fibroblast growth factor receptor signaling pathway IGI
IGI: Inferred from genetic interaction
18669637 GOA
acts upstream of or within positive regulation of vascular permeability IDA
IDA: Inferred from direct assay
18669637 GOA
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
18669637 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FGFBP3 Protein Structure

FGF-BP1

FGF-BP1: FGF binding protein 1 (FGF-BP1) (13 - 258)

  • 0
  • 100
  • 200
  • 258 a.a.
Protein Preferred Names Protein Names

fibroblast growth factor-binding protein 3

  • FGF-binding protein 3

Recombinant FGFBP3 Proteins

Cat. No. Product Name Accession Purity
HY-P76926 FGFBP3 Protein, Human (sf9, His) Q8TAT2 (R27-G258) ≥ 85%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Spinal Muscular Atrophy, Type Iv

  • SMA4

  • Spinal Muscular Atrophy, Adult Form

  • Spinal Muscular Atrophy 4

  • Spinal Muscular Atrophy-4

  • Adult Spinal Muscular Atrophy

  • Spinal Muscular Atrophy, Proximal, Adult, Autosomal Recessive

  • Proximal Spinal Muscular Atrophy Type 4

  • Sma Type 4

  • Sma Type Iv

  • Sma-Iv

  • Sma Iv

  • Spinal Muscular Atrophy Adult Form

  • Spinal Muscular Atrophy Proximal Adult Autosomal Recessive

  • Spinal Muscular Atrophy Type Iv

  • Atrophy, Muscular, Spinal, Type Iv

  • Myelopathic Muscular Atrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04910 FGFBP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19776 Fgfbp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26273 Fgfbp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus FGFBP3 MGD MGI:1919764
Rattus norvegicus FGFBP3 RGD RGD:1560326
Canis familiaris FGFBP3 VGNC VGNC:40855
Bos taurus FGFBP3 VGNC VGNC:28984
Macaca mulatta FGFBP3 VGNC VGNC:106049
Others FGFBP3 NCBI