Gabrr1 - gamma-aminobutyric acid (GABA) C receptor, subunit rho 1 Gene

Also Known as GABA-C

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14408

Summary

Enables ligand-gated ion channel activity involved in regulation of presynaptic membrane potential and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in several processes, including chemical synaptic transmission; chloride transmembrane transport; and regulation of membrane potential. Predicted to act upstream of or within chloride transport. Located in glutamatergic synapse. Is active in GABA-ergic synapse. Is expressed in brain; cerebral cortex; and retina. Orthologous to human GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1). [provided by Alliance of Genome Resources, Apr 2022]

Gabrr1 Products (1)

mRNA Protein Name
NM_008075.2 NP_032101.3 gamma-aminobutyric acid receptor subunit rho-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential EXP
EXP: Inferred from Experiment
23583111 MGI
enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential IDA
IDA: Inferred from direct assay
23583111 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
30902970 MGI
Biological Process GO Annotation Evidence References Source
involved in modulation of chemical synaptic transmission EXP
EXP: Inferred from Experiment
12019334 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
12019334 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
12019334 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
12019334 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
12019334 MGI
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
12019334 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
12019334 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
12019334 MGI
is active in intracellular vesicle IDA
IDA: Inferred from direct assay
30902970 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
25422464 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
23583111 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-aminobutyric acid receptor subunit rho-1

  • GABA(A) receptor subunit rho-1

  • GABA(C) receptor

  • gamma-aminobutyric acid (GABA-A) receptor, subunit rho 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05225 GABRR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gabrr1 NCBI NCBI:2569