Gcm1 - glial cells missing homolog 1 Gene

Also Known as GCMa; glide; Gcm-rs2; Gcm1-rs1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14531

Summary

Enables DNA binding activity and zinc ion binding activity. Acts upstream of or within several processes, including astrocyte fate commitment; embryonic placenta development; and positive regulation of syncytium formation by plasma membrane fusion. Located in nucleus. Is expressed in several structures, including extraembryonic component; limb; metanephros; placenta; and thymus. Orthologous to human GCM1 (glial cells missing transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Gcm1 Products (1)

mRNA Protein Name
NM_008103.3 NP_032129.2 chorion-specific transcription factor GCMa

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12297286 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21558372 MGI
enables zinc ion binding IDA
IDA: Inferred from direct assay
12297286 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within astrocyte fate commitment IDA
IDA: Inferred from direct assay
14573516 MGI
acts upstream of or within branching involved in labyrinthine layer morphogenesis IMP
IMP: Inferred from mutant phenotype
10888880 MGI
acts upstream of or within cell differentiation involved in embryonic placenta development IMP
IMP: Inferred from mutant phenotype
10888880 MGI
acts upstream of or within positive regulation of syncytium formation by plasma membrane fusion IGI
IGI: Inferred from genetic interaction
21558372 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
23610556 MGI
acts upstream of syncytium formation by plasma membrane fusion IGI
IGI: Inferred from genetic interaction
21558372 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
14573516 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chorion-specific transcription factor GCMa

  • GCM motif protein 1

  • Gcm 1

  • Gcm a

  • glial cell deficient

  • mGCM1

  • mGCMa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130229 (±)5,6-DHET lactone / Unkown
HY-RS05335 GCM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gcm1 NCBI NCBI:8521