Gcnt1 - glucosaminyl (N-acetyl) transferase 1, core 2 Gene

Also Known as IGnT; C2GNT; C2GnT-L; C2GlcNAcT; B130048E03; C2 GlcNAcT; 5630400D21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14537

Summary

Predicted to enable beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity. Acts upstream of or within kidney morphogenesis and tissue morphogenesis. Predicted to be located in Golgi cisterna; extracellular space; and trans-Golgi network. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeleton. Orthologous to human GCNT1 (glucosaminyl (N-acetyl) transferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Gcnt1 Products (3)

mRNA Protein Name
NM_001136484.3 NP_001129956.3 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
NM_010265.5 NP_034395.4 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
NM_173442.5 NP_775618.3 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity IDA
IDA: Inferred from direct assay
12954635 MGI
Biological Process GO Annotation Evidence References Source
involved in O-glycan processing, core 2 IMP
IMP: Inferred from mutant phenotype
9881978 MGI
acts upstream of or within kidney morphogenesis IGI
IGI: Inferred from genetic interaction
19349303 MGI
involved in positive regulation of leukocyte tethering or rolling IMP
IMP: Inferred from mutant phenotype
9881978 MGI
acts upstream of or within tissue morphogenesis IGI
IGI: Inferred from genetic interaction
19349303 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

  • beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (Core 2 branching enzyme) (Core2-GlcNAc-transferase) (C2GNT)

  • core 2 beta-1,6-N-acetylglucosaminyltransferase

  • core 2-branching enzyme

  • core2-GlcNAc-transferase

  • leukocyt

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05339 GCNT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gcnt1 NCBI NCBI:2650