Gja4 - gap junction protein, alpha 4 Gene

Also Known as Cx37; Cnx37; Cxnh1; Gja-4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14612

Summary

Predicted to enable gap junction channel activity. Acts upstream of or within blood vessel development. Predicted to be located in gap junction. Predicted to be part of connexin complex. Is expressed in several structures, including central nervous system; gonad; heart; intestine; and vascular system. Human ortholog(s) of this gene implicated in coronary artery disease and myocardial infarction. Orthologous to human GJA4 (Gap Junction Protein alpha 4). [provided by Alliance of Genome Resources, Apr 2022]

Gja4 Products (1)

mRNA Protein Name
NM_008120.3 NP_032146.1 gap junction alpha-4 protein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within blood vessel development IMP
IMP: Inferred from mutant phenotype
12435353 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction alpha-4 protein

  • connexin h1

  • connexin-37

  • gap junction membrane channel protein alpha 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05443 GJA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gja4 NCBI NCBI:2701