Glra4 - glycine receptor, alpha 4 subunit Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14657

Summary

Enables extracellularly glycine-gated Chloride Channel activity. Involved in chloride transmembrane transport and response to amino acid. Is integral component of postsynaptic specialization membrane. Is active in glycinergic synapse. Is expressed in brain. Orthologous to human GLRA4 (glycine receptor alpha 4 (pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]

Glra4 Products (1)

mRNA Protein Name
NM_010297.2 NP_034427.2 glycine receptor subunit alpha-4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables extracellularly glycine-gated chloride channel activity IDA
IDA: Inferred from direct assay
10762330 MGI
Biological Process GO Annotation Evidence References Source
involved in chloride transmembrane transport IDA
IDA: Inferred from direct assay
10762330 MGI
involved in response to amino acid IDA
IDA: Inferred from direct assay
10762330 MGI
Cellular Component GO Annotation Evidence References Source
is active in glycinergic synapse IDA
IDA: Inferred from direct assay
17154252 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10762330 MGI
is active in postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
17154252 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycine receptor subunit alpha-4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05389 GFRA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05492 GLRA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05493 GLRA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05494 GLRA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22528 Glra1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29048 Glra1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Glra4 NCBI NCBI:441509