CBLN2 - cerebellin 2 precursor Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 147381

About CBLN2

Cytogenetic location: 18q22.3 Genomic coordinates (GRCh38): 18:72,536,681-72,638,521 (from NCBI)

This gene has 9 transcripts (splice variants), 228 orthologues and 3 paralogues. Biased expression in brain (RPKM 6.0), small intestine (RPKM 0.7) and 3 other tissues.

Summary

Predicted to be involved in maintenance of synapse structure and spontaneous synaptic transmission. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in extracellular space. Predicted to be active in glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2022]

CBLN2 Products (1)

mRNA Protein Name
NM_182511.4 NP_872317.1 cerebellin-2 precursor

CBLN2 Protein Structure

C1q

C1q: C1q domain (94 - 221)

  • 0
  • 100
  • 200
  • 224 a.a.
Protein Preferred Names Protein Names

cerebellin-2

Recombinant CBLN2 Proteins

Cat. No. Product Name Accession Purity
HY-P79253 Cerebellin-2 Protein, Human (CHO, HA) Q8IUK8 (R50-L224) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Ischiocoxopodopatellar Syndrome With Or Without Pulmonary Arterial Hypertension

  • Small Patella Syndrome

  • Ischiopatellar Dysplasia

  • Coxopodopatellar Syndrome

  • Scott-Taor Syndrome

  • Sps

  • Ischiocoxopodopatellar Syndrome

  • Patella Aplasia, Coxa Vara, And Tarsal Synostosis

  • ICPPS

  • Congenital Coxa Vara, Patella Aplasia And Tarsal Synostosis

  • Coxo-Podo-Patellar Syndrome

  • Patella Aplasia, Coxa Vara, Tarsal Synostosis

  • Coxopodipatellar Syndrome
Pulmonary Venoocclusive Disease

  • Pulmonary Veno-Occlusive Disease

  • Obstructive Disease Of The Pulmonary Veins

  • Pvod

  • Isolated Pulmonary Venous Sclerosis

  • Venous Form Of Primary Pulmonary Hypertension

  • Pulmonary Venoocclusive Disease 1, Autosomal Dominant
Pseudohypoaldosteronism, Type I, Autosomal Recessive

  • Autosomal Recessive Pseudohypoaldosteronism Type 1

  • PHA1B

  • Pseudohypoaldosteronism Type 1

  • Pseudohypoaldosteronism, Type I

  • Generalized Pha1

  • Generalized Pseudohypoaldosteronism Type 1

  • Pseudohypoaldosteronism Type 1 Autosomal Recessive

  • Pha1

  • Pseudohypoaldosteronism

  • Pha I, Autosomal Recessive

  • Autosomal Recessive Pha 1

  • Pseudohypoaldosteronism Type 1, Recessive

  • Pseudohypoaldosteronism Type I

  • Autosomal Recessive Pha1

  • Pha Type 1

  • Pseudohypoaldosteronism 1, Autosomal Recessive

  • Multisystem Pseudohypoaldosteronism

  • Pha Type I, Autosomal Recessive

  • Pseudohypoaldosteronism Type I, Autosomal Recessive
Gilles De La Tourette Syndrome

  • Tourette Syndrome

  • Tourette Disorder

  • GTS

  • Ts

  • Gilles De La Tourette'S Syndrome

  • Motor-Verbal Tic Disorder

  • Guinon'S Disease

  • Psychogenic Tics

  • Tourette'S Syndrome

  • Chronic Motor And Vocal Tic Disorder

  • Td

  • Tourette'S Disease

  • Combined Vocal And Multiple Motor Tic Disorder [De La Tourette]

  • Combined Vocal And Multiple Motor Tic Disorder

  • Tic De La Tourette
Hereditary Hemorrhagic Telangiectasia

  • Rendu-Osler-Weber Disease

  • Hht

  • Osler-Weber-Rendu Disease

  • Telangiectasia, Hereditary Hemorrhagic

  • Osler Hemorrhagic Telangiectasia Syndrome

  • Orw Disease

  • Osler Weber Rendu Syndrome

  • Osler-Rendu-Weber Disease

  • Osler-Weber-Rendu Syndrome

  • Rendu-Osler Disease

  • Telangiectasia Hereditary Hemorrhagic

  • Telangiectasia Hemorrhagic, Hereditary

  • Hht - [Hereditary Haemorrhagic Telangiectasia]

  • Osler Haemorrhagic Telangiectasia Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02002 CBLN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CBLN2 VGNC VGNC:107698
Macaca mulatta CBLN2 VGNC VGNC:70557
Mus musculus CBLN2 MGD MGI:88282
Canis familiaris CBLN2 VGNC VGNC:38762
Bos taurus CBLN2 VGNC VGNC:26812
Rattus norvegicus CBLN2 RGD RGD:1309715
Others CBLN2 NCBI