C1orf127 - chromosome 1 open reading frame 127 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 148345

About C1orf127

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:10,946,475-10,982,076 (from NCBI)

This gene has 5 transcripts (splice variants) and 72 orthologues. Broad expression in stomach (RPKM 1.3), pancreas (RPKM 0.6) and 15 other tissues.

Summary

Predicted to be involved in heart development. Predicted to act upstream of or within determination of left/right symmetry. [provided by Alliance of Genome Resources, Apr 2022]

C1orf127 Products (2)

mRNA Protein Name
NM_001170754.2 NP_001164225.1 uncharacterized protein C1orf127 isoform 1 precursor
NM_001366227.2 NP_001353156.1 uncharacterized protein C1orf127 isoform 2

C1orf127 Protein Structure

DUF4556

DUF4556: Domain of unknown function (DUF4556) (151 - 365)

  • 0
  • 200
  • 400
  • 600
  • 823 a.a.
Protein Preferred Names Protein Names

uncharacterized protein C1orf127

Related Diseases

Diseases Alias
Joubert Syndrome 10

  • JBTS10

  • Joubert Syndrome, Type 10
Schnyder Corneal Dystrophy

  • Schnyder Crystalline Corneal Dystrophy

  • SCCD

  • Corneal Dystrophy, Crystalline, Of Schnyder

  • Corneal Dystrophy, Schnyder Type

  • Corneal Dystrophy Crystalline Of Schnyder

  • Crystalline Stromal Dystrophy

  • Hereditary Crystalline Stromal Dystrophy Of Schnyder

  • Scd

  • Corneal Dystrophy, Schnyder

  • Schnyder Crystalline Dystrophy Sine Crystals

  • Dystrophy, Corneal, Crystalline, Schnyder
Joubert Syndrome 25

  • JBTS25

  • Joubert Syndrome, Type 25
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01712 C1orf127 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta C1orf127 VGNC VGNC:70405
Mus musculus C1orf127 MGD MGI:2685418
Rattus norvegicus C1orf127 RGD RGD:1585063
Others C1orf127 NCBI