C1orf127 - chromosome 1 open reading frame 127 Gene

Homo sapiens

Gene ID: 148345 | Gene type: protein coding

About C1orf127

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:10,946,475-10,982,076 (from NCBI)

This gene has 5 transcripts (splice variants) and 72 orthologues. Broad expression in stomach (RPKM 1.3), pancreas (RPKM 0.6) and 15 other tissues.

Summary

Predicted to be involved in heart development. Predicted to act upstream of or within determination of left/right symmetry. [provided by Alliance of Genome Resources, Apr 2022]

C1orf127 Products(2)

mRNA	Protein	Name
NM_001170754.2	NP_001164225.1	uncharacterized protein C1orf127 isoform 1 precursor
NM_001366227.2	NP_001353156.1	uncharacterized protein C1orf127 isoform 2

C1orf127 Protein Structure

DUF4556

0
200
400
600
823 a.a.

Protein Preferred Names

Protein Names

uncharacterized protein C1orf127

Related Diseases

Diseases

Alias

Joubert Syndrome 10

JBTS10

Joubert Syndrome, Type 10

Schnyder Corneal Dystrophy

Schnyder Crystalline Corneal Dystrophy	SCCD
Corneal Dystrophy, Crystalline, Of Schnyder	Corneal Dystrophy, Schnyder Type
Corneal Dystrophy Crystalline Of Schnyder	Crystalline Stromal Dystrophy
Hereditary Crystalline Stromal Dystrophy Of Schnyder	Scd
Corneal Dystrophy, Schnyder	Schnyder Crystalline Dystrophy Sine Crystals
Dystrophy, Corneal, Crystalline, Schnyder

Joubert Syndrome 25

JBTS25

Joubert Syndrome, Type 25

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01712	C1orf127 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	C1orf127	VGNC	VGNC:70405
Mus musculus	C1orf127	MGD	MGI:2685418
Rattus norvegicus	C1orf127	RGD	RGD:1585063

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