2. Gene
  3. Guk1 - guanylate kinase 1 Gene

Guk1 - guanylate kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gmk; Guk-1

Gene ID: 14923 | Gene type: protein coding

About Guk1

Summary

Enables ATP binding activity and guanylate kinase activity. Involved in purine nucleotide metabolic process. Located in cytosol and photoreceptor inner segment. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human GUK1 (guanylate kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Guk1 Products(7)

mRNA Protein Name
NM_001159410.2 NP_001152882.1 guanylate kinase isoform 2
NM_001403833.1 NP_001390762.1 guanylate kinase isoform 2
NM_001403834.1 NP_001390763.1 guanylate kinase isoform 2
NM_001403835.1 NP_001390764.1 guanylate kinase isoform 3
NM_001403836.1 NP_001390765.1 guanylate kinase isoform 3
NM_001403837.1 NP_001390766.1 guanylate kinase isoform 4
NM_008193.4 NP_032219.2 guanylate kinase isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ATP binding IDA
IDA: Inferred from direct assay
12036965 MGI
enables guanylate kinase activity IDA
IDA: Inferred from direct assay
8663313 MGI
Biological Process GO Annotation Evidence Reference Source
involved in purine nucleotide metabolic process IDA
IDA: Inferred from direct assay
8663313 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
29515371 MGI
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
29515371 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanylate kinase

GMP kinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05924 GUK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Guk1 NCBI NCBI:2987