Hnrnpl - heterogeneous nuclear ribonucleoprotein L Gene

Also Known as Hnrpl; D830027H13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15388

Summary

Enables RNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Located in pronucleus. Is expressed in several structures, including central nervous system; early conceptus; sensory organ; tail unsegmented mesenchyme; and tooth. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and systemic scleroderma. Orthologous to human HNRNPL (heterogeneous nuclear ribonucleoprotein L). [provided by Alliance of Genome Resources, Apr 2022]

Hnrnpl Products (6)

mRNA Protein Name
NM_001402935.1 NP_001389864.1 heterogeneous nuclear ribonucleoprotein L isoform a
NM_001402936.1 NP_001389865.1 heterogeneous nuclear ribonucleoprotein L isoform c
NM_001402937.1 NP_001389866.1 heterogeneous nuclear ribonucleoprotein L isoform c
NM_001402938.1 NP_001389867.1 heterogeneous nuclear ribonucleoprotein L isoform d
NM_001402939.1 NP_001389868.1 heterogeneous nuclear ribonucleoprotein L isoform d
NM_177301.6 NP_796275.3 heterogeneous nuclear ribonucleoprotein L isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
27315481 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8871564 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
22523384 MGI
Cellular Component GO Annotation Evidence References Source
located in pronucleus IDA
IDA: Inferred from direct assay
7768196 MGI
is active in synapse EXP
EXP: Inferred from Experiment
25211037 MGI
is active in synapse IDA
IDA: Inferred from direct assay
25211037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heterogeneous nuclear ribonucleoprotein L

  • hnRNP L

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06274 HNRNPL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hnrnpl NCBI NCBI:3191