Hoxa5 - homeobox A5 Gene

Mus musculus

Also known as Hox-1.3

Gene ID: 15402 | Gene type: protein coding

About Hoxa5

Summary

Enables DNA binding activity. Acts upstream of or within several processes, including animal organ development; intestinal epithelial cell maturation; and respiratory system process. Located in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; gut; and skeleton. Orthologous to human HOXA5 (homeobox A5). [provided by Alliance of Genome Resources, Apr 2022]

Hoxa5 Products(1)

mRNA	Protein	Name
NM_010453.5	NP_034583.1	homeobox protein Hox-A5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	7911971	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	20599664	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within anterior/posterior pattern specification	IGI IGI: Inferred from genetic interaction	17626057	MGI
acts upstream of or within anterior/posterior pattern specification	IMP IMP: Inferred from mutant phenotype	7901120	MGI
acts upstream of or within bronchiole development	IMP IMP: Inferred from mutant phenotype	9441679	MGI
acts upstream of or within cartilage morphogenesis	IMP IMP: Inferred from mutant phenotype	9441679	MGI
acts upstream of or within cell migration	IMP IMP: Inferred from mutant phenotype	17003488	MGI
acts upstream of or within cell-cell signaling involved in mammary gland development	IMP IMP: Inferred from mutant phenotype	16607641	MGI
acts upstream of or within embryonic skeletal system development	IGI IGI: Inferred from genetic interaction	17626057	MGI
acts upstream of or within embryonic skeletal system morphogenesis	IMP IMP: Inferred from mutant phenotype	7901120	MGI
acts upstream of or within epithelial tube branching involved in lung morphogenesis	IMP IMP: Inferred from mutant phenotype	9441679	MGI
acts upstream of or within intestinal epithelial cell maturation	IMP IMP: Inferred from mutant phenotype	10564089	MGI
acts upstream of or within lobar bronchus epithelium development	IMP IMP: Inferred from mutant phenotype	9441679	MGI
acts upstream of or within lung alveolus development	IMP IMP: Inferred from mutant phenotype	15295088	MGI
acts upstream of or within lung development	IMP IMP: Inferred from mutant phenotype	17417799	MGI
acts upstream of or within lung goblet cell differentiation	IMP IMP: Inferred from mutant phenotype	17003488	MGI
acts upstream of or within lung-associated mesenchyme development	IMP IMP: Inferred from mutant phenotype	9441679	MGI
acts upstream of or within mammary gland alveolus development	IMP IMP: Inferred from mutant phenotype	16607641	MGI
acts upstream of or within mammary gland epithelial cell differentiation	IMP IMP: Inferred from mutant phenotype	16607641	MGI
acts upstream of or within mesenchymal-epithelial cell signaling	IMP IMP: Inferred from mutant phenotype	16607641	MGI
acts upstream of or within morphogenesis of an epithelium	IMP IMP: Inferred from mutant phenotype	9441679	MGI
acts upstream of or within multicellular organism growth	IMP IMP: Inferred from mutant phenotype	12815622	MGI
acts upstream of or within pattern specification process	IMP IMP: Inferred from mutant phenotype	11900462	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	8635464	MGI
acts upstream of or within regulation of mammary gland epithelial cell proliferation	IMP IMP: Inferred from mutant phenotype	16607641	MGI
acts upstream of or within respiratory gaseous exchange by respiratory system	IMP IMP: Inferred from mutant phenotype	15295088	MGI
acts upstream of or within respiratory system process	IMP IMP: Inferred from mutant phenotype	9441679	MGI
acts upstream of or within skeletal system development	IMP IMP: Inferred from mutant phenotype	11900462	MGI
acts upstream of or within thyroid gland development	IMP IMP: Inferred from mutant phenotype	12815622	MGI
acts upstream of or within trachea cartilage morphogenesis	IMP IMP: Inferred from mutant phenotype	9441679	MGI
acts upstream of or within trachea morphogenesis	IMP IMP: Inferred from mutant phenotype	9441679	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	2890554	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

homeobox protein Hox-A5

homeo box A5	homeobox protein Hox-1.3
homeobox protein M2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06300	HOXA5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hoxa5	NCBI	NCBI:3202

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