Hspa1l - heat shock protein 1-like Gene

Also Known as Msh5; Hsc70t

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15482

Summary

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and misfolded protein binding activity. Acts upstream of or within binding activity of sperm to zona pellucida. Located in cell body. Part of zona pellucida receptor complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and limb segment. Human ortholog(s) of this gene implicated in Kawasaki disease; major depressive disorder; schizophrenia; systemic lupus erythematosus; and uveitis. Orthologous to human HSPA1L (heat shock protein family A (HSP70) member 1 like). [provided by Alliance of Genome Resources, Apr 2022]

Hspa1l Products (1)

mRNA Protein Name
NM_013558.2 NP_038586.2 heat shock 70 kDa protein 1-like

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within binding of sperm to zona pellucida IDA
IDA: Inferred from direct assay
21880732 MGI
Cellular Component GO Annotation Evidence References Source
located in cell body IDA
IDA: Inferred from direct assay
21880732 MGI
part of zona pellucida receptor complex IDA
IDA: Inferred from direct assay
21880732 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heat shock 70 kDa protein 1-like

  • heat shock 70 kDa protein 1L

  • heat shock 70 kDa-like protein 1

  • heat shock 70kDa protein 1-like

  • heat shock protein cognate 70, testis

  • heat shock-related protein hsc70t

  • inducible heat shock protein 70

  • spermatid-specific heat shock protein 70

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06426 HSPA1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hspa1l NCBI NCBI:3305