HSPA1L - heat shock protein family A (Hsp70) member 1 like Gene

Homo sapiens

Also known as HSP70T; hum70t; HSP70-1L; HSP70-HOM

Gene ID: 3305 | Gene type: protein coding

About HSPA1L

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,809,619-31,815,283 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 110 orthologues and 13 paralogues. Biased expression in testis (RPKM 35.8) and ovary (RPKM 2.3).

Summary

This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008]

HSPA1L Products(1)

mRNA	Protein	Name
NM_005527.4	NP_005518.3	heat shock 70 kDa protein 1-like

HSPA1L Protein Structure

HSP70

0
100
200
300
400
500
600
641 a.a.

Protein Preferred Names

Protein Names

heat shock 70 kDa protein 1-like

epididymis secretory sperm binding protein

Related Diseases

Diseases

Alias

Uveoparotid Fever

Heerfordt'S Syndrome

Anthracosis

Black Lung	Coal Workers' Pneumoconiosis
Melanoedema	Black Lung Disease
Pneumoconiosis	Coal Miner'S Pneumoconiosis
Coal Workers' Lung	Coal Worker'S Pneumoconiosis
Coal Workers Pneumoconiosis	Coal Miners' Lung
Coal Miners' Pneumoconiosis	Coal Pneumoconiosis
Colliers' Anthracosis	Colliers' Lung
Lung Melanosis	Miners' Asthma
Miners' Lung	Pneumomelanosis
Cwp - [Coalworkers Pneumoconiosis]	Fibrosis Of Lung With Anthracosilicosis
Lung Fibrosis With Anthracosis	Miners' Pneumoconiosis
Carbon Lung	Coalworker Lung
Collier'S Asthma	Anthracosilicosis
Lung Anthracosis

Visceral Leishmaniasis

Kala-Azar	Leishmaniasis, Visceral
Infection By Visceral Leishmaniasis	Leishmaniasis Visceral
Sahib Disease	Ponos
Burdwan Fever	Mard El Bicha
Sirkari Disease	Indian Visceral Leishmaniasis
Dumdum Fever	Visceral Leishmaniasis Due To Leishmania Donovani

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06426	HSPA1L Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	HSPA1L	RGD	RGD:1595925
Mus musculus	HSPA1L	MGD	MGI:96231
Macaca mulatta	HSPA1L	VGNC	VGNC:81079

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