1. Gene
  2. TRIM38 - tripartite motif containing 38 Gene

TRIM38 - tripartite motif containing 38 Gene

Homo sapiens

Also known as RNF15; RORET

Gene ID: 10475 | Gene type: protein coding

About TRIM38

This gene has 1 transcript (splice variant), 103 orthologues and 80 paralogues. Ubiquitous expression in spleen (RPKM 9.0), lymph node (RPKM 8.4) and 24 other tissues.

Summary

This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012]

TRIM38 Products(1)

mRNA Protein Name
NM_006355.5 NP_006346.1 E3 ubiquitin-protein ligase TRIM38

TRIM38 Protein Structure

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (16 - 62)

zf-B_box

zf-B_box: B-box zinc finger (89 - 127)

PRY

PRY: SPRY-associated domain (294 - 342)

SPRY

SPRY: SPRY domain (344 - 452)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 465 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM38

RING-type E3 ubiquitin transferase TRIM38

Related Diseases

Diseases Alias
Fanconi Renotubular Syndrome 2

FRTS2

Fanconi Renotubular Syndrome, Type 2

Acute Promyelocytic Leukemia

Leukemia, Acute Promyelocytic

Acute Myeloblastic Leukemia Type 3

Aml M3

APL

Leukemia, Acute Promyelocytic, Somatic

Aml With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Apml

Acute Myeloblastic Leukemia 3

Acute Myeloid Leukemia With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Acute Myeloblastic Leukaemia Type 3

Acute Myeloid Leukaemia M3

Acute Myeloid Leukemia M3

Acute Promyelocytic Leukaemia

M3 Anll

Myeloid Leukemia, Acute, M3

Leukemia Promyelocytic Acute

Leukemia, Promyelocytic, Acute

Leukemia, Acute, Promyelocytic

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta TRIM38 VGNC VGNC:78548
Bos taurus TRIM38 VGNC VGNC:36333
Rattus norvegicus TRIM38 RGD RGD:1596868
Canis familiaris TRIM38 VGNC VGNC:47819
Felis catus TRIM38 VGNC VGNC:66537
Mus musculus TRIM38 MGD MGI:2684869
Others TRIM38 NCBI