2. Gene
  3. Hsd11b2 - hydroxysteroid 11-beta dehydrogenase 2 Gene

Hsd11b2 - hydroxysteroid 11-beta dehydrogenase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 11HSD2

Gene ID: 15484 | Gene type: protein coding

About Hsd11b2

Summary

Predicted to enable NAD binding activity and steroid binding activity. Acts upstream of or within female pregnancy. Predicted to be located in cytoplasm; lipid droplet; and nucleoplasm. Is expressed in several structures, including adrenal gland; ear; genitourinary system; hemolymphoid system; and nervous system. Human ortholog(s) of this gene implicated in apparent mineralocorticoid excess syndrome; hypertension; inherited metabolic disorder; obesity; and type 1 diabetes mellitus. Orthologous to human HSD11B2 (hydroxysteroid 11-beta dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Hsd11b2 Products(1)

mRNA Protein Name
NM_008289.2 NP_032315.2 11-beta-hydroxysteroid dehydrogenase type 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within female pregnancy IMP
IMP: Inferred from mutant phenotype
23677469 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

11-beta-hydroxysteroid dehydrogenase type 2

11-DH2

11-beta-HSD2

NAD-dependent 11-beta-hydroxysteroid dehydrogenase

corticosteroid 11-beta-dehydrogenase isozyme 2

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14598 Diethylstilbestrol 99.62% Unkown
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06388 HSD11B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsd11b2 NCBI NCBI:3291