Hsd11b2 - hydroxysteroid 11-beta dehydrogenase 2 Gene

Also Known as 11HSD2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15484

Summary

Predicted to enable NAD binding activity and steroid binding activity. Acts upstream of or within female pregnancy. Predicted to be located in cytoplasm; lipid droplet; and nucleoplasm. Is expressed in several structures, including adrenal gland; ear; genitourinary system; hemolymphoid system; and nervous system. Human ortholog(s) of this gene implicated in apparent mineralocorticoid excess syndrome; hypertension; inherited metabolic disorder; obesity; and type 1 diabetes mellitus. Orthologous to human HSD11B2 (hydroxysteroid 11-beta dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Hsd11b2 Products (1)

mRNA Protein Name
NM_008289.2 NP_032315.2 11-beta-hydroxysteroid dehydrogenase type 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within female pregnancy IMP
IMP: Inferred from mutant phenotype
23677469 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

11-beta-hydroxysteroid dehydrogenase type 2

  • 11-DH2

  • 11-beta-HSD2

  • NAD-dependent 11-beta-hydroxysteroid dehydrogenase

  • corticosteroid 11-beta-dehydrogenase isozyme 2

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14598 Diethylstilbestrol 99.62% Unkown

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06388 HSD11B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W744064 Diethylstilbestrol-d4 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsd11b2 NCBI NCBI:3291