Hsp90ab1 - heat shock protein 90 alpha (cytosolic), class B member 1 Gene

Also Known as 90kDa; Hsp84; Hsp90; Hspcb; Hsp84-1

Species: Mus musculus

Gene Type: protein coding

Gene ID: 15516

Summary

Enables protein folding chaperone; protein kinase binding activity; and Tau Protein binding activity. Contributes to protein kinase regulator activity. Involved in several processes, including axonogenesis; positive regulation of protein kinase B signaling; and regulation of cellular protein metabolic process. Acts upstream of or within cellular response to interleukin-4; negative regulation of apoptotic process; and placenta development. Located in growth cone; neuronal cell body; and perinuclear region of cytoplasm. Part of HSP90-CDC37 chaperone complex. Is expressed in several structures, including branchial arch; central nervous system; eye; limb; and placenta. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human HSP90AB1 (heat shock protein 90 alpha family class B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Hsp90ab1 Products (1)

mRNA	Protein	Name
NM_008302.3	NP_032328.2	heat shock protein HSP 90-beta

Protein Preferred Names	Protein Names
heat shock protein HSP 90-beta	HSP 84 TSTA heat shock 84 kDa heat shock 90kDa protein 1, beta heat shock protein 1, beta heat shock protein 90kDa alpha (cytosolic), class B member 1 heat shock protein, 84 kDa 1 retinal degeneration slow protein tumor-specific transplantation 84

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-123035	Gamendazole	Inhibitor	99.44%	Unkown
HY-RS06418	HSP90AB1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-N7521	Procyanidin C2		/	Unkown
HY-RS18017	Hsp90ab1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24490	Hsp90ab1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hsp90ab1	NCBI	NCBI:3326