FAAH2 - fatty acid amide hydrolase 2 Gene
Also Known as AMDD
Species: Homo sapiens
About FAAH2
This gene has 3 transcripts (splice variants), 160 orthologues and 2 paralogues. Ubiquitous expression in liver (RPKM 2.5), skin (RPKM 1.5) and 24 other tissues.
Summary
This gene encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of Enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl Amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
FAAH2 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001353840.1 | NP_001340769.1 | fatty-acid amide hydrolase 2 isoform 2 |
| NM_001353841.1 | NP_001340770.1 | fatty-acid amide hydrolase 2 isoform 3 |
| NM_174912.4 | NP_777572.2 | fatty-acid amide hydrolase 2 isoform 1 |
FAAH2 Protein Structure
Amidase: Amidase (69 - 513)
- 0
- 100
- 200
- 300
- 400
- 500
- 532 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
fatty-acid amide hydrolase 2 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Developmental And Epileptic Encephalopathy 28 |
|
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