Il11ra1 - interleukin 11 receptor, alpha chain 1 Gene

Also Known as NR1; GP130; Il11ra; Il-11ra; Il11ra2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16157

Summary

Enables interleukin-11 binding activity and interleukin-11 receptor activity. Acts upstream of or within several processes, including cytokine-mediated signaling pathway; decidualization; and natural killer cell differentiation. Predicted to be located in extracellular region and membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; cranial suture; genitourinary system; immune system; and musculature. Orthologous to human IL11RA (interleukin 11 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il11ra1 Products (3)

mRNA Protein Name
NM_001163401.1 NP_001156873.1 interleukin-11 receptor subunit alpha-1 precursor
NM_001172054.1 NP_001165525.1 interleukin-11 receptor subunit alpha-1 precursor
NM_010549.3 NP_034679.1 interleukin-11 receptor subunit alpha-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables interleukin-11 binding IPI
IPI: Inferred from physical interaction
7957045 MGI
enables interleukin-11 receptor activity IDA
IDA: Inferred from direct assay
7957045 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of cell population proliferation IDA
IDA: Inferred from direct assay
7957045 MGI
acts upstream of or within cytokine-mediated signaling pathway IDA
IDA: Inferred from direct assay
7957045 MGI
acts upstream of or within decidualization IMP
IMP: Inferred from mutant phenotype
9500603 MGI
acts upstream of or within maternal process involved in female pregnancy IMP
IMP: Inferred from mutant phenotype
9500603 MGI
acts upstream of or within natural killer cell differentiation IMP
IMP: Inferred from mutant phenotype
15499555 MGI
acts upstream of or within placenta development IMP
IMP: Inferred from mutant phenotype
9679067 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
7957045 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-11 receptor subunit alpha-1

  • IL-11 receptor subunit alpha-1

  • IL-11R subunit alpha-1

  • IL-11R-alpha-1

  • IL-11RA1

  • Il-11ra-alpha

  • NR-1

  • enhancer trap locus homolog 2

  • etl-2

  • interleukin 11 receptor, alpha chain 2

  • locus 2

  • novel cytokine receptor 1

Recombinant Il11ra1 Proteins

Cat. No. Product Name Accession Purity
HY-P70860 IL-11R alpha Protein, Mouse (HEK293, His) Q64385 (S24-Q367) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06676 IL11RA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06688 IL13RA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174638 Human IL13RA1 mRNA / Unkown
HY-174643 Human IL11RA mRNA / Unkown
HY-RS19279 Il13ra1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25769 Il13ra1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown