Inhbb - inhibin beta-B Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16324

Summary

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Homozygous knockout mice for this gene exhibit eyelid defects. [provided by RefSeq, Aug 2016]

Inhbb Products (1)

mRNA Protein Name
NM_008381.4 NP_032407.1 inhibin beta B chain preproprotein

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of apoptotic signaling pathway IGI
IGI: Inferred from genetic interaction
20454446 MGI
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
19491194 MGI
involved in cellular response to leptin stimulus IEP
IEP: Inferred from expression pattern
19491194 MGI
involved in cellular response to starvation IEP
IEP: Inferred from expression pattern
19491194 MGI
involved in fat cell differentiation IEP
IEP: Inferred from expression pattern
19491194 MGI
acts upstream of or within negative regulation of insulin secretion IMP
IMP: Inferred from mutant phenotype
18480258 MGI
acts upstream of or within oocyte development IGI
IGI: Inferred from genetic interaction
20454446 MGI
acts upstream of or within positive regulation of apoptotic signaling pathway IGI
IGI: Inferred from genetic interaction
20454446 MGI
involved in positive regulation of ovulation IMP
IMP: Inferred from mutant phenotype
17609433 MGI
Cellular Component GO Annotation Evidence References Source
located in cell periphery IDA
IDA: Inferred from direct assay
8133077 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
8133077 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inhibin beta B chain

  • activin beta-B chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06814 INHBB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19015 Inhbb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25504 Inhbb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990454 Anti-INHBB/Activin B Antibody 95.09% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Inhbb NCBI NCBI:3625