Irx1 - Iroquois homeobox 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16371

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within proximal/distal pattern formation involved in metanephric nephron development and specification of loop of Henle identity. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; autopod; central nervous system; genitourinary system; and sensory organ. Orthologous to human IRX1 (iroquois homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Irx1 Products (1)

mRNA Protein Name
NM_010573.2 NP_034703.2 iroquois-class homeodomain protein IRX-1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in metanephros development IEP
IEP: Inferred from expression pattern
17875669 MGI
involved in proximal/distal pattern formation involved in metanephric nephron development IEP
IEP: Inferred from expression pattern
17875669 MGI
involved in specification of loop of Henle identity IEP
IEP: Inferred from expression pattern
17875669 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

iroquois-class homeodomain protein IRX-1

  • Iroquois related homeobox 1

  • homeodomain protein IRXA1

  • iroquois homeobox protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06920 IRX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06922 IRX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Irx1 NCBI NCBI:79192