Kif17 - kinesin family member 17 Gene

Mus musculus

Also known as Kif17b; mKIAA1405; 5930435E01Rik

Gene ID: 16559 | Gene type: protein coding

About Kif17

Summary

Enables microtubule motor activity. Involved in anterograde dendritic transport of neurotransmitter receptor complex. Acts upstream of or within microtubule-based process; protein-containing complex localization; and vesicle-mediated transport. Located in cytoskeleton; periciliary membrane compartment; and photoreceptor connecting cilium. Part of intraciliary transport particle B and Kinesin complex. Is expressed in central nervous system; retina; and testis. Orthologous to human KIF17 (Kinesin family member 17). [provided by Alliance of Genome Resources, Apr 2022]

Kif17 Products(2)

mRNA	Protein	Name
NM_001190978.1	NP_001177907.1	kinesin-like protein KIF17 isoform 2
NM_010623.4	NP_034753.1	kinesin-like protein KIF17 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables microtubule motor activity	IDA IDA: Inferred from direct assay	10846156	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	16257958	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in anterograde dendritic transport of neurotransmitter receptor complex	IDA IDA: Inferred from direct assay	22514311	MGI
involved in anterograde dendritic transport of neurotransmitter receptor complex	IMP IMP: Inferred from mutant phenotype	22514311	MGI
acts upstream of or within microtubule-based process	IDA IDA: Inferred from direct assay	10846156	MGI
acts upstream of or within protein-containing complex localization	IMP IMP: Inferred from mutant phenotype	17174564	MGI
acts upstream of or within vesicle-mediated transport	IDA IDA: Inferred from direct assay	10846156	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in axoneme	IDA IDA: Inferred from direct assay	19384852	MGI
located in ciliary basal body	IDA IDA: Inferred from direct assay	19384852	MGI
located in cilium	IDA IDA: Inferred from direct assay	25243405	MGI
part of kinesin complex	IDA IDA: Inferred from direct assay	10846156	MGI
located in microtubule cytoskeleton	IDA IDA: Inferred from direct assay	19384852	MGI
located in periciliary membrane compartment	IDA IDA: Inferred from direct assay	19384852	MGI
located in photoreceptor connecting cilium	IDA IDA: Inferred from direct assay	19384852	MGI
located in photoreceptor inner segment	IDA IDA: Inferred from direct assay	19384852	MGI
located in photoreceptor outer segment	IDA IDA: Inferred from direct assay	19384852	MGI
is active in postsynapse	IDA IDA: Inferred from direct assay	35678994	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

kinesin-like protein KIF17

N-4 kinesin

kinesin 17

Kif17 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Kif17	Q99PW8	Kcnd2	Mus musculus	Q9Z0V2	IF	16257958
Intra	Kif17	Q99PW8	Kcnd2	Mus musculus	Q9Z0V2	Anti Bait CoIP	16257958
Intra	Kif17	Q99PW8	Kcnd2	Mus musculus	Q9Z0V2	Anti Tag CoIP	16257958

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07266	KIF17 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Kif17	NCBI	NCBI:57576

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