2. Gene
  3. TRIM60 - tripartite motif containing 60 Gene

TRIM60 - tripartite motif containing 60 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RNF33; RNF129

Gene ID: 166655 | Gene type: protein coding

About TRIM60

Cytogenetic location: 4q32.3 Genomic coordinates (GRCh38): 4:165,031,999-165,041,749 (from NCBI)

This gene has 5 transcripts (splice variants), 37 orthologues and 80 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Pseudogenes of this gene are located on more than six chromosomes including chromosome 4. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013]

TRIM60 Products(2)

mRNA Protein Name
NM_001258025.2 NP_001244954.1 tripartite motif-containing protein 60
NM_152620.3 NP_689833.1 tripartite motif-containing protein 60

TRIM60 Protein Structure

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (16 - 56)

zf-B_box

zf-B_box: B-box zinc finger (93 - 133)

PRY

PRY: SPRY-associated domain (297 - 345)

SPRY

SPRY: SPRY domain (347 - 460)

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  • 471 a.a.
Protein Preferred Names Protein Names

tripartite motif-containing protein 60

ring finger protein 129

Related Diseases

Diseases Alias
Hypotrichosis-Lymphedema-Telangiectasia-Renal Defect Syndrome

Glomerulonephritis With Sparse Hair And Telangiectases

Telangiectatic Membranoproliferative Glomerulonephritis

HLTRS

Hypotrichosis-Lymphedema-Telangiectasia-Membranoproliferative Glomerulonephritis Syndrome

Hlt-Renal Defect Syndrome

Glomerulonephritis Sparse Hair Telangiectases
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15061 TRIM60 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TRIM60 VGNC VGNC:80069
Mus musculus TRIM60 MGD MGI:2387430
Rattus norvegicus TRIM60 RGD RGD:2324264
Macaca mulatta TRIM60 VGNC VGNC:100286