Krt4 - keratin 4 Gene

Also Known as K4; Krt2-4; Krt-2.4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16682

Summary

Involved in epithelial cell differentiation and negative regulation of epithelial cell proliferation. Predicted to be located in cell surface and keratin filament. Is expressed in several structures, including alimentary system; lower urinary tract; sensory organ; skin; and trachea. Used to study hereditary mucosal leukokeratosis. Human ortholog(s) of this gene implicated in hereditary mucosal leukokeratosis. Orthologous to human KRT4 (keratin 4). [provided by Alliance of Genome Resources, Apr 2022]

Krt4 Products (1)

mRNA Protein Name
NM_008475.2 NP_032501.2 keratin, type II cytoskeletal 4

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
9727004 MGI
involved in negative regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
9727004 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

keratin, type II cytoskeletal 4

  • 57kDa keratin

  • 57kd keratin

  • CK-4

  • cytokeratin-4

  • cytoskeletal 57 kDa keratin

  • keratin complex 2, basic, gene 4

  • type-II keratin Kb4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07455 KRT4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Krt4 NCBI NCBI:3851