PRSS35 - serine protease 35 Gene

Also Known as C6orf158; dJ223E3.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 167681

About PRSS35

This gene has 1 transcript (splice variant), 266 orthologues and 1 paralogue. Broad expression in ovary (RPKM 5.2), brain (RPKM 3.9) and 14 other tissues.

Summary

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PRSS35 Products (2)

mRNA Protein Name
NM_001170423.2 NP_001163894.1 inactive serine protease 35 precursor
NM_153362.3 NP_699193.2 inactive serine protease 35 precursor
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27499296 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRSS35 Protein Structure

Trypsin

Trypsin: Trypsin (140 - 202)

  • 0
  • 100
  • 200
  • 300
  • 413 a.a.
Protein Preferred Names Protein Names

inactive serine protease 35

  • protease, serine 35

PRSS35 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PRSS35 Q8N3Z0 C1QBP Homo sapiens Q07021 27499296
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Pontocerebellar Hypoplasia, Type 6
  • Pontocerebellar Hypoplasia Type 6

  • PCH6

  • Fatal Infantile Encephalopathy With Mitochondrial Respiratory Chain Defects

  • Encephalopathy, Fatal Infantile, With Mitochondrial Respiratory Chain Defects

  • Encephalopathy Fatal Infantile With Mitochondrial Respiratory Chain Defects

  • Pontocerebellar Hypoplasia 6

  • Hypoplasia, Pontocerebellar, Type 6

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PRSS35 RGD RGD:1311282
Macaca mulatta PRSS35 VGNC VGNC:76299
Canis familiaris PRSS35 VGNC VGNC:45066
Felis catus PRSS35 VGNC VGNC:64398
Bos taurus PRSS35 VGNC VGNC:33418
Mus musculus PRSS35 MGD MGI:2444800
Others PRSS35 NCBI