2. Gene
  3. Lhx4 - LIM homeobox protein 4 Gene

Lhx4 - LIM homeobox protein 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gsh4; Gsh-4; A330062J17Rik

Gene ID: 16872 | Gene type: protein coding

About Lhx4

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and methyl-CpG binding activity. Acts upstream of or within several processes, including negative regulation of apoptotic process; neuron differentiation; and placenta development. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in panhypopituitarism. Orthologous to human LHX4 (LIM homeobox 4). [provided by Alliance of Genome Resources, Apr 2022]

Lhx4 Products(1)

mRNA Protein Name
NM_010712.2 NP_034842.2 LIM/homeobox protein Lhx4
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within animal organ morphogenesis IMP
IMP: Inferred from mutant phenotype
12183375 MGI
acts upstream of apoptotic process IMP
IMP: Inferred from mutant phenotype
12183375 MGI
acts upstream of or within medial motor column neuron differentiation IGI
IGI: Inferred from genetic interaction
9865699 MGI
acts upstream of or within motor neuron axon guidance IGI
IGI: Inferred from genetic interaction
9865699 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
12183375 MGI
acts upstream of or within placenta development IGI
IGI: Inferred from genetic interaction
18425848 MGI
Cellular Component GO Annotation Evidence Reference Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
10482234 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

LIM/homeobox protein Lhx4

LIM homeo box protein 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07634 LHX4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lhx4 NCBI NCBI:89884