Lhx5 - LIM homeobox protein 5 Gene

Also Known as Lim2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16873

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription, DNA-templated and spinal cord association neuron differentiation. Acts upstream of or within brain development and cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation. Predicted to be active in nucleus. Is expressed in several structures, including future brain; limb; nervous system; sensory organ; and urinary system. Orthologous to human LHX5 (LIM homeobox 5). [provided by Alliance of Genome Resources, Apr 2022]

Lhx5 Products (1)

mRNA Protein Name
NM_008499.5 NP_032525.1 LIM/homeobox protein Lhx5

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell proliferation in forebrain IMP
IMP: Inferred from mutant phenotype
10325223 MGI
acts upstream of or within cell-cell signaling IGI
IGI: Inferred from genetic interaction
17664423 MGI
acts upstream of or within cerebellar Purkinje cell differentiation IGI
IGI: Inferred from genetic interaction
17664423 MGI
acts upstream of or within cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation IGI
IGI: Inferred from genetic interaction
17664423 MGI
acts upstream of or within cerebellum development IGI
IGI: Inferred from genetic interaction
17664423 MGI
acts upstream of or within forebrain neuron differentiation IMP
IMP: Inferred from mutant phenotype
10325223 MGI
acts upstream of or within hippocampus development IMP
IMP: Inferred from mutant phenotype
10325223 MGI
acts upstream of or within neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
10325223 MGI
involved in positive regulation of DNA-templated transcription IGI
IGI: Inferred from genetic interaction
17166926 MGI
acts upstream of or within regulation of neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
10325223 MGI
involved in spinal cord association neuron differentiation IGI
IGI: Inferred from genetic interaction
17166926 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

LIM/homeobox protein Lhx5

  • LIM homeo box protein 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07635 LHX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20764 Lhx5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27278 Lhx5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lhx5 NCBI NCBI:64211