1. Gene
  2. Lhx8 - LIM homeobox protein 8 Gene

Lhx8 - LIM homeobox protein 8 Gene

Mus musculus

Also known as L3; Lhx7

Gene ID: 16875 | Gene type: protein coding

About Lhx8

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within animal organ development and learning or memory. Located in female germ cell nucleus. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; nervous system; and respiratory system. Orthologous to human LHX8 (LIM homeobox 8). [provided by Alliance of Genome Resources, Apr 2022]

Lhx8 Products(5)

mRNA Protein Name
NM_001410060.1 NP_001396989.1 LIM/homeobox protein Lhx8 isoform 2
NM_001410061.1 NP_001396990.1 LIM/homeobox protein Lhx8 isoform 2
NM_001410062.1 NP_001396991.1 LIM/homeobox protein Lhx8 isoform 3
NM_001410063.1 NP_001396992.1 LIM/homeobox protein Lhx8 isoform 3
NM_010713.3 NP_034843.2 LIM/homeobox protein Lhx8 isoform 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within female gonad development IMP
IMP: Inferred from mutant phenotype
16690745 MGI
acts upstream of or within forebrain neuron development IGI
IGI: Inferred from genetic interaction
15217369 MGI
acts upstream of or within forebrain neuron differentiation IMP
IMP: Inferred from mutant phenotype
15978004 MGI
acts upstream of or within learning or memory IMP
IMP: Inferred from mutant phenotype
15978004 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IMP
IMP: Inferred from mutant phenotype
12703558 MGI
Cellular Component GO Annotation Evidence Reference Source
located in female germ cell nucleus IDA
IDA: Inferred from direct assay
18753606 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

LIM/homeobox protein Lhx8

LIM homeo box protein 8

LIM homeobox protein 7

LIM/homeobox protein Lhx7

Orthologs Information

Species Symbol Source ID
Homo sapiens Lhx8 NCBI NCBI:431707