Lhx8 - LIM homeobox protein 8 Gene

Also Known as L3; Lhx7

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16875

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within animal organ development and learning or memory. Located in female germ cell nucleus. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; nervous system; and respiratory system. Orthologous to human LHX8 (LIM homeobox 8). [provided by Alliance of Genome Resources, Apr 2022]

Lhx8 Products (5)

mRNA Protein Name
NM_001410060.1 NP_001396989.1 LIM/homeobox protein Lhx8 isoform 2
NM_001410061.1 NP_001396990.1 LIM/homeobox protein Lhx8 isoform 2
NM_001410062.1 NP_001396991.1 LIM/homeobox protein Lhx8 isoform 3
NM_001410063.1 NP_001396992.1 LIM/homeobox protein Lhx8 isoform 3
NM_010713.3 NP_034843.2 LIM/homeobox protein Lhx8 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within female gonad development IMP
IMP: Inferred from mutant phenotype
16690745 MGI
acts upstream of or within forebrain neuron development IGI
IGI: Inferred from genetic interaction
15217369 MGI
acts upstream of or within forebrain neuron differentiation IMP
IMP: Inferred from mutant phenotype
15978004 MGI
acts upstream of or within learning or memory IMP
IMP: Inferred from mutant phenotype
15978004 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IMP
IMP: Inferred from mutant phenotype
12703558 MGI
Cellular Component GO Annotation Evidence References Source
located in female germ cell nucleus IDA
IDA: Inferred from direct assay
18753606 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

LIM/homeobox protein Lhx8

  • LIM homeo box protein 8

  • LIM homeobox protein 7

  • LIM/homeobox protein Lhx7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07637 LHX8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lhx8 NCBI NCBI:431707