Arr3 - arrestin 3, retinal Gene

Also Known as Car; Arr4; Carr; Carfl

Species: Mus musculus

Gene Type: protein coding
Gene ID: 170735

Summary

Enables opsin binding activity and phosphoprotein binding activity. Acts upstream of or within endocytosis and regulation of protein phosphorylation. Located in photoreceptor outer segment and synapse. Is expressed in retina. Human ortholog(s) of this gene implicated in myopia. Orthologous to human ARR3 (Arrestin 3). [provided by Alliance of Genome Resources, Apr 2022]

Arr3 Products (1)

mRNA Protein Name
NM_133205.3 NP_573468.1 arrestin-C

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables opsin binding IDA
IDA: Inferred from direct assay
12486395 MGI
enables phosphoprotein binding IDA
IDA: Inferred from direct assay
12486395 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20375344 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within endocytosis IDA
IDA: Inferred from direct assay
15218143 MGI
acts upstream of or within regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
15218143 MGI
acts upstream of or within regulation of protein phosphorylation IGI
IGI: Inferred from genetic interaction
15218143 MGI
Cellular Component GO Annotation Evidence References Source
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
10725384 MGI
located in synapse IDA
IDA: Inferred from direct assay
12486395 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

arrestin-C

  • X-arrestin

  • arrestin 4

  • retinal cone arrestin-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01027 ARR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20857 Arrb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arr3 NCBI NCBI:407