Znrf1 - zinc and ring finger 1 Gene

Also Known as Rnf42; Zrfp1; nin283; B830022L21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 170737

Summary

Enables ubiquitin protein Ligase activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein K48-linked ubiquitination. Predicted to be located in cytosol; endosome; and membrane. Is expressed in central nervous system; genitourinary system; and retina nuclear layer. Orthologous to human ZNRF1 (zinc and ring finger 1). [provided by Alliance of Genome Resources, Apr 2022]

Znrf1 Products (6)

mRNA Protein Name
NM_001168621.3 NP_001162092.1 E3 ubiquitin-protein ligase ZNRF1 isoform a
NM_001168622.3 NP_001162093.1 E3 ubiquitin-protein ligase ZNRF1 isoform b
NM_001168623.2 NP_001162094.1 E3 ubiquitin-protein ligase ZNRF1 isoform c
NM_001363488.2 NP_001350417.1 E3 ubiquitin-protein ligase ZNRF1 isoform a
NM_001363489.1 NP_001350418.1 E3 ubiquitin-protein ligase ZNRF1 isoform c
NM_133206.5 NP_573469.1 E3 ubiquitin-protein ligase ZNRF1 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
22057101 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
22057101 MGI
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
22057101 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
22057101 MGI
involved in protein K48-linked ubiquitination IDA
IDA: Inferred from direct assay
22057101 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase ZNRF1

  • RING-type E3 ubiquitin transferase ZNRF1

  • nerve injury-induced gene 283 protein

  • peripheral nerve injury protein nin283

  • ring finger protein 42

  • zinc ring finger protein 1

  • zinc/RING finger protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS16183 ZNRF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Znrf1 NCBI NCBI:84937