Inpp5j - inositol polyphosphate 5-phosphatase J Gene

Also Known as Pipp; Pib5pa

Species: Mus musculus

Gene Type: protein coding
Gene ID: 170835

Summary

Enables phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity. Acts upstream of or within negative regulation of neuron projection development and negative regulation of peptidyl-serine phosphorylation. Located in dendritic shaft; growth cone; and plasma membrane. Is expressed in alimentary system; ear; nervous system; respiratory system; and skeleton. Orthologous to human INPP5J (inositol polyphosphate-5-phosphatase J). [provided by Alliance of Genome Resources, Apr 2022]

Inpp5j Products (1)

mRNA Protein Name
NM_172439.3 NP_766027.2 phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity IDA
IDA: Inferred from direct assay
16280363 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of neuron projection development IDA
IDA: Inferred from direct assay
16280363 MGI
acts upstream of or within negative regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
16280363 MGI
acts upstream of or within negative regulation of peptidyl-serine phosphorylation IDA
IDA: Inferred from direct assay
16280363 MGI
acts upstream of or within negative regulation of peptidyl-serine phosphorylation IMP
IMP: Inferred from mutant phenotype
16280363 MGI
Cellular Component GO Annotation Evidence References Source
located in dendritic shaft IDA
IDA: Inferred from direct assay
16280363 MGI
located in growth cone IDA
IDA: Inferred from direct assay
16280363 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
16280363 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

  • phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A

  • proline-rich inositol polyphosphate 5-phosphatase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06832 INPP5J Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Inpp5j NCBI NCBI:27124