Fbxo32 - F-box protein 32 Gene

Also Known as MAFbx; Atrogin1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171043

Summary

Predicted to enable ubiquitin-protein transferase activity. Involved in muscle atrophy; positive regulation of cardiac muscle cell apoptotic process; and regulation of muscle adaptation. Predicted to be located in Z disc; cytosol; and nucleoplasm. Predicted to be part of SCF ubiquitin Ligase complex. Predicted to be active in cytoplasm and nucleus. Used to study muscular atrophy. Orthologous to human FBXO32 (F-box protein 32). [provided by Alliance of Genome Resources, Apr 2022]

Fbxo32 Products (1)

mRNA Protein Name
NM_133521.2 NP_598205.2 F-box only protein 32

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in muscle atrophy IDA
IDA: Inferred from direct assay
11679633 RGD
involved in negative regulation of cardiac muscle hypertrophy IMP
IMP: Inferred from mutant phenotype
24117217 RGD
involved in positive regulation of cardiac muscle cell apoptotic process IGI
IGI: Inferred from genetic interaction
24117217 RGD
involved in response to electrical stimulus involved in regulation of muscle adaptation IDA
IDA: Inferred from direct assay
21465538 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-box only protein 32

  • atrogin-1

  • atrophy gene 1

  • muscle atrophy F-box protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04804 FBXO32 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20156 Fbxo32 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26660 Fbxo32 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbxo32 NCBI NCBI:114907