Inpp5j - inositol polyphosphate-5-phosphatase J Gene

Also Known as Inpp; Pipp; Pib5pa

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171088

Summary

Enables inositol-polyphosphate 5-phosphatase activity. Involved in negative regulation of microtubule polymerization and negative regulation of neuron projection development. Located in cytoplasm; growth cone; and ruffle. Is extrinsic component of membrane. Orthologous to human INPP5J (inositol polyphosphate-5-phosphatase J). [provided by Alliance of Genome Resources, Apr 2022]

Inpp5j Products (1)

mRNA Protein Name
NM_133562.2 NP_598246.1 phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables inositol-polyphosphate 5-phosphatase activity IDA
IDA: Inferred from direct assay
10593988 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of microtubule polymerization IMP
IMP: Inferred from mutant phenotype
16280363 RGD
involved in negative regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
16280363 RGD
Cellular Component GO Annotation Evidence References Source
located in growth cone IDA
IDA: Inferred from direct assay
16280363 RGD
located in ruffle IDA
IDA: Inferred from direct assay
10593988 RGD
located in ruffle membrane IDA
IDA: Inferred from direct assay
10593988 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

  • proline-rich inositol polyphosphate 5-phosphatase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06832 INPP5J Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Inpp5j NCBI NCBI:27124